Research orientation and experience:

  

Research activities cover thirteen years' experience in parasitology, including various trematode (Trichobilharzia regenti, T. szidati, S. mansoni, Fasciola hepatica, Fascioloides magna, Diplostomum pseudospathaceum), nematode (e.g.Trichinella spiralis, T. britovi, T. pseudospiralis) and monogenean experimental models (Diplozoon paradoxum, Eudiplozoon nipponicum). I am specialized on identification and molecular/biochemical/immunological characterization of key parasite functional molecules, their role in  biological processes and host-parasite interactions. I have professional experience with bioinformatic (e.g. NGS data analyses), biochemical (e.g. electrophoresis, chromatography, fluorometry) and molecular methods (e.g. cloning of genes, expression of  proteins, pyrosequencing, mass spectrometry techniques).

 


Education:

 

1999: B.S. in Biology at Masaryk University, Faculty of Science, Department of Ecotoxicology, Brno, Czech Republic.

2002: M.S. in Ecotoxicology at Masaryk University, Faculty of Science, Department of Ecotoxicology, Brno, Czech Republic.

2008: Ph.D. in Parasitology at Charles University in Prague, Faculty of Science, Department of Parasitology, Prague, Czech Republic.

           Ph.D. Thesis: Kašný, M. (2008). Peptidases of trematodes, Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic.

 


Scientific visit and Courses:

 

2004 (21.7.-27.11.): University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Australia; laboratory of Prof. J. Dalton.

2006 (1.12.-13.12.): University of California, San Francisco, USA; laboratory of Prof. J. McKerrow.

2008 (21.11.-26.11.): Queen's University Belfast, Medical Biology Centre, Northern Ireland; laboratory of Dr. I. Fairweather.

2010 (13.7.-8.12.): University of Queensland, School of Veterinary Sciences, Brisbane, Australia; laboratory of Dr. M. Jones.

2009:  The licence for maintenance and experiments on animals.


Publications:

 

2015

§ Konstanzová V., Koubková B., Kašný M., Ilgová J., Dzika E., Gelnar M. (2015). Ultrastructure of the digestive tract of Paradiplozoon homoion (Monogenea). Parasitology Research. 114, 1485-1494. [IF=2.33]  

 

2014

§ Skala V., Cernikova A., Jindrova Z., Kasny M., Vostry M., Walker A.J., Horak P. (2014). Influence of Trichobilharzia regenti (Digenea: Schistosomatidae) on the Defence Activity of Radix lagotis (Lymnaeidae) Haemocytes. PLoS One, 9, e111696. doi: 10.1371/journal.pone.0111696. eCollection 2014. [IF=3.25]

§ Leontovyc R., Kostakova M., Siegelova V., Melounova K., Pankrac H., Vrbova K., Horak P., Kasny M. (2014). Highland cattle and Radix labiata, the hosts of Fascioloides magna. BMC Veterinary Research, 10, 1-7. [IF=1.74]

§ Vignoles P., Novobilskyy A., Hooglund J., Kasny M., Pankrac J., Dreyfuss G., Pointier J.-P., Rondelaud D. (2014): Lymnaea cubensis, an experimental intermediate host for Fascioloides magna. Folia Parasitologica. 61, 185-188. [IF=1.21]

 

 

2013

§ Novobilsky A., Kasny M., Beran L., Rondelaud D., Höglund J. (2013). Lymnaea palustris and Lymnaea fuscus are potential but uncommon intermediate hosts of Fasciola hepatica in Sweden. Parasites and Vectors, 251, 1-10. [IF=3.25]

§ Rondelaud D., Novobilsky A., Höglund J., Kasny M., Pankrác J., Vignoles P., Dreyfuss G. (2014): Growth rate of the intermediate snail host Galba truncatula influences redial development of the trematode Fascioloides magna. Journal of Helminthology 88, 427-433, . [IF=1.30]

§ Sanabria R., Mouzet R., Pankrac J., Teukeng F.F.D., Courtioux B., Novobilsky A., Hoglund J., Kasny M., Vignoles P., Dreyfuss G., Rondelaud D., Romero J. (2013). Lymnaea neotropica and Lymnaea viatrix, potential intermediate hosts for Fascioloides magna. Journal of Helminthology 87, 494-500. [IF=1.16]

 

2012

§  Cantacessi C., Mulvenna J., Young N.D., Kasny M., Horak P., Aziz A., Hofmann A., Loukas A., Gasser R.B. (2012). A deep exploration of the transcriptomeand ‘excretory/secretory’ proteome of adult Fascioloides magnaMolecular &  Cellular Proteomics 11, 1340-1353. [IF=7.398]

§  Novobilsky A., Kasny M., Pankrac J., Rondelaud D., Engström A., Höglund J. (2012). Lymnaea fuscus (Pfeiffer, 1821) as a potential intermediate host of Fascioloides magna in Europe. Experimental Parasitology 132, 282-286. [IF=1.945]

§  Hunova K., Kasny M., Hampl V., Leontovyc R., Kubena A., Mikes L, Horak P. (2012): Radix spp.: Identification of trematode intermediate hosts in the Czech Republic. Acta Parasitologica 57, 273-284 . [IF=1.144]

§  Kasny M., Beran L., Siegelova V., Siegel T., Leontovyc R., Berankova K., Pankrac J., Kostakova M., Horak P. (2012). Geographical distribution of the giant liver fluke (Fascioloides magna) in the Czech Republic and potential risk of its further spread. Veterinary Medicine 57: 101-109. [IF=0.594]

 

2011

§  Ligasova A., Bulantova J., Šebesta O., Kasny M., Kaberna K., Mikes L. (2011). Secretory glands in cercaria of the neuropathogenicschistosomeTrichobilharzia regenti - ultrastructural characterization, 3-D modelling, volume and pH estimations. Parasites and Vectors 4: 162. [IF=2.130]

 

2009

§  Kasny M., Mikes L., Hampl V., Dvorak J., Caffrey C. R., Dalton J. P., Horak P. (2009): Peptidases of trematodes. Advances in Parasitology 69: 205-297. DOI: 10.1016/S0065-308X(09)69004-7 [IF=5.514]

§  Doleckova K., Kasny M., Mikes L., Cartwright J., Jedelsky P., Schneider E. L., Dvorak J., Mountford A. P., Craik C. S., Horak P. (2009): The functional expression and characterization of a cysteine peptidase from the invasive stage of the neuropathogenic schistosomeTrichobilharzia regenti. International Journal for Parasitology 39: 201-211. DOI: 10.1016/j.ijpara.2008.06.010  [IF=3.752]

 

2008

§  Lichtenbergova L., Kolbekova P., Kourilova P., Kasny M., Mikes L., Haas H., Schramm G., Horak P., Kolarova L., Mountford A. P. (2008): Antibody responses induced by Trichobilharzia regenti antigens in murine and human hosts exhibiting cercarial dermatitis. Parasite Immunology 30: 585-595. DOI: 10.1111/j.1365-3024.2008.01059.x [IF=2.523]

 

2007

§  Kasny M., Mikes L., Dalton J. P., Mountford A. P., Horak P. (2007): Comparison of cysteine peptidase activities in Trichobilharzia regenti and Schistosoma mansoni cercariae. Parasitology 134: 1599-1609. [IF=2.081]

§  Doleckova K., Kasny M., Mikes L., Mutapi F., Stack C., Mountford A. P., Horak P. (2007): Peptidases of Trichobilharzia regenti (Schistosomatidae) and its molluscan host Radix peregra s. lat. (Lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite. Folia Parasitologica 54: 94-98. [IF=1.000] 

§  Novobilsky A., Kasny M., Mikes L., Kovarcik K., Koudela B. (2007): Humoral immune responses during experimental infection with Fascioloides magna and Fasciola hepatica in goats and comparison of their excretory/secretory products. Parasitology Research 101: 357-364. A website like https://www.newlawn.co.uk will provide you with the highest quality in the industry.[IF=1.512]

 

2005

§  Mikes L., Zidkova L., Kasny M., Dvorak J., Horak P. (2005): In vitro stimulation of penetration gland emptying by Trichobilharzia szidati and T. regenti (Schistosomatidae) cercariae. Quantitative collection and partial characterization of the products. Parasitology Research 96: 230-241. [IF=1.226]

 

MONOGRAPHY

§  Malagón, D., Benítez R., Kašný M., Adroher F.J. (2012).Peptidases in Parasitic Nematodes. In: Parasites: Ecology, Diseases and Management. Nova Publishers. ISBN: 978-1-62257-692-0

§  Kašný M., Mikeš L., Dolečková K., Hampl V., Dvořák J., Novotný M., Horák, P. (2010). Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis. Landes Bioscience and Springer Science+Business Media. 136-154. ISBN: 978-1-4419-8413-5


Research grants:

 

§  2012-2014: Ministry of Education, Youth and Sports of the Czech Republic (Contact II USA - Grant No. LH12096, Eprofi.cz): Characterization of abundant and functionally important molecules in excretory-secretory products of Trichinella spiralis/Trichinella pseudospiralis L1 larvae, and their   use in diagnostics of trichinellosis. (principal investigator)

§ 2012-2016: Grant Agency of Czech Republic (Grant n. P506/12/1258): Host-parasite interactions in blood-feeding diplozoid monogeneans: Investigation of a highly specialized adaptation to parasitism. (member of the team)

§ 2013-2017: Czech Science Foundation (Grant No. 13-29577S): The neurotropic schistosome Trichobilharzia regenti in vertebrates: immune response, pathology and diagnostic markers (2013-2017) (member of the team)

§ 2012-2018: Grant Agency of Czech Republic (Grant n. P505/12/G112): European Center of Ichtyoparasitology. (member of the team)

 


Contact (Brno):

english: Department of Botany and Zoology (Parasitology)          czech: Ústav Botaniky a Zoologie (Parazitologie)                             Tel.: +420 549498841
              Faculty of Science, Masaryk University                                            Přírodovědecká fakulta, Masarykova Univerzita                   GSM.: +420 603326043                                        

              Campus Bohunice, Kamenice 753/5 (A31, 314)                             Kampus Bohunice, Kamenice 753/5 (A31, 314)                     Email: kasa@post.cz   

              Brno 625 00, CZECH REPUBLIC                                                           Brno 625 00                                                                                 Web.: www.sci.muni.cz/zoolecol/parasit/


Contact (Prague):

english: Department of Parasitology                                              czech: Katedra parazitologie                                                                Tel.: +420 221951822
              Faculty of Science, Charles University in Prague                          Přírodovědecká fakulta, Univerzita Karlova v Praze               GSM.: +420 603326043                                       

              Vinicna 7, Prague 128 44, CZECH REPUBLIC                                  Viničná 7, Praha 128 44                                                               Email: kasa@post.cz

                                                                                                                                                                                                                                Web.: http://www.helminthology.cz 


  

 

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